ARP1149-01 [Polyclonal Antibody]
CIDEA Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species:   Rabbit
Applications:   WB IF
Immunogen Range:   Recombinant protein of human CIDEA
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1149
Swiss Prot:   O60543
Synonyms:   CIDE-A
Purification:   Affinity purification
Storage:   Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Caculated MW:   25 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IF 1:50-1:100
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information