Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | Recombinant protein of human YWHAQ |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 10971 |
Swiss Prot: | P27348 |
Synonyms: | 1C5, HS1, 14-3-3 |
Purification: | Affinity purification |
Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. |
Caculated MW: | 28 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100 |
Reacitivity: | Human, Mouse, Rat |