Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | Recombinant protein of human OAS2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4939 |
Swiss Prot: | P29728 |
Synonyms: | / |
Purification: | Affinity purification |
Storage: | Store at -20℃ (regular) or -80℃ (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
Caculated MW: | 82 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
Reacitivity: | Human, Mouse |