
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | Recombinant protein of human OAS2 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 4939 |
| Swiss Prot: | P29728 |
| Synonyms: | / |
| Purification: | Affinity purification |
| Storage: | Store at -20℃ (regular) or -80℃ (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Caculated MW: | 82 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reacitivity: | Human, Mouse |