ARP10891-51 [Polyclonal Antibody]
PPARGC1A Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB ELISA IP IF
Immunogen Range:   A synthetic peptide corresponding to amino acids 1-300 mapping at the N-terminus of human PPARGC1A
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   10891
Swiss Prot:   Q9UBK2
Synonyms:   LEM6, PGC1, PGC1A, PGC-1v, PPARGC1, PGC-1(alpha)
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Caculated MW:   90 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IF 1:50-1:500
Reacitivity:   Chicken, Cow, Dog, Horse, Human, Mouse, Pig, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information