Species: | Mouse |
Applications: | WB IHC ICC |
Immunogen Range: | A synthetic peptide of human BCL2 |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 |
GENE ID: | 596 |
Swiss Prot: | P10415 |
Synonyms: | Bcl-2, PPP1R50 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. |
Caculated MW: | 22 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:400 IHC 1:50-1:200 ICC 1:100-1:500 |
Reacitivity: | Human |