ARP3091-31 [Polyclonal Antibody]
HIF1A Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide of human HIF1A
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   3091
Swiss Prot:   Q16665
Synonyms:   HIF1, MOP1, PASD8, HIF-1A, bHLHe78, HIF-1alpha, HIF1-ALPHA
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Caculated MW:   93 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:400
Reacitivity:   Human, Mouse, Rabbit, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information