ARP7099-31
[Polyclonal Antibody]
TLR4 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC ICC |
| Immunogen Range: | A synthetic peptide of human TLR4 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 7099 |
| Swiss Prot: | O00206 |
| Synonyms: | TOLL, CD284, TLR-4, ARMD10 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Caculated MW: | 96 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:400 IHC 1:50-1:200 ICC 1:100-1:500 |
| Reacitivity: | Human, Mouse, Rabbit, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information