Species: | Rabbit |
Applications: | WB IHC ELISA IP IF ICC |
Immunogen Range: | A synthetic peptide corresponding to residues surrounding amino acids 161 of human CLEC7A |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 64581 |
Swiss Prot: | Q9BXN2 |
Synonyms: | BGR, CLECSF12, DECTIN1 |
Purification: | Affinity purification |
Storage: | Store at -20°C. For long term storage store at -80°C in PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal).Avoid freeze/thaw cycles. |
Background: | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq |
Caculated MW: | 28 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:500 IHC 1:100-1:500 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse, Rat |