ARP1277-31 [Polyclonal Antibody]
COL1A1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ICC
Immunogen Range:   A recombinant protein of human COL1A1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1277
Swiss Prot:   P02452
Synonyms:   OI4
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Caculated MW:   180 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:400
IHC 1:50-1:200
ICC 1:100-1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information