ARP4001-31 [Polyclonal Antibody]
LMNB1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ICC
Immunogen Range:   A recombinant protein of human LMNB1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   4001
Swiss Prot:   P20700
Synonyms:   LMN, ADLD, LMN2, LMNB
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
Caculated MW:   66 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:400
IHC 1:50-1:200
ICC 1:100-1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information