
| Species: | Rabbit |
| Applications: | WB IHC ELISA IF ICC |
| Immunogen Range: | A synthetic peptide derived from human TBX5 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 69110 |
| Swiss Prot: | Q99593 |
| Synonyms: | HOS |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. |
| Caculated MW: | 50 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:500 IHC 1:100-1:500 IF 1:100-1:500 ICC 1:100-1:500 |
| Reacitivity: | Human |