ARP7422-31 [Polyclonal Antibody]
VEGFA Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ICC
Immunogen Range:   A recombinant protein of human VEGFA
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   7422
Swiss Prot:   P15692
Synonyms:   VPF, VEGF, MVCD1
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Caculated MW:   27 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:400
IHC 1:50-1:200
ICC 1:100-1:500
Reacitivity:   Human, Mouse, Rabbit, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information