ARM7431-24C [Monoclonal Antibody]
VIM Rabbit Monoclonal Antibody (Alexa Fluor(R) 647 Conjugate)
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Species:   Rabbit
Applications:   IF FC
Immunogen Range:   A synthetic peptide corresponding to residues surrounding Arg45 of human vimentin protein This antibody was conjugated to Alexa Fluor® 647 under optimal conditions with an F/P ratio of 2-6 The Alexa Fluor® 647 dye is maximally excited by red light (eg 633
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   7431
Swiss Prot:   P08670
Synonyms:   CTRCT30, Vimentin
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
Caculated MW:   57 kDa
Observed MW:   Refer to Figures
Applications:   IF 1:400
FC 1:50
Reacitivity:   Human, Monkey, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information