ARP6885-31
[Polyclonal Antibody]
MAP3K7 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC ELISA IF |
| Immunogen Range: | A synthetic peptide derived from human MAP3K7 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 6885 |
| Swiss Prot: | O43318 |
| Synonyms: | TAK1, MEKK7, TGF1a |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Caculated MW: | 67 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:500 IHC 1:100-1:500 IF 1:100-1:500 |
| Reacitivity: | Chicken, Cow, Horse, Human, Mouse, Pig, Rabbit, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information