HRP842-21S [Polyclonal Antibody]
CASP9 Rabbit Polyclonal Antibody (Human Specific)
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Species:   Rabbit
Applications:   WB FC
Immunogen Range:   A synthetic peptide corresponding to residues surrounding aspartic acid 315 of human caspase-9
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   842
Swiss Prot:   P55211
Synonyms:   APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.
Caculated MW:   35, 37, 47 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
FC 1:100
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information