ARMM016P-21 [Monoclonal Antibody]
Phospho-Ser CDKs Substrate Rabbit Monoclonal Antibody
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Species:   Rabbit
Applications:   WB IP
Immunogen Range:   A synthetic phospho-CDK substrate peptide library The antibody is formulated from two rabbit monoclones in order to cover a broad range of reactivity
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   /
Swiss Prot:   /
Synonyms:   /
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Cyclin-dependent kinases (CDKs) are a family of Ser/Thr kinases that regulate cell-cycle transitions through their association and subsequent phosphorylation of targets in a strictly ordered fashion (1). The substrates for CDKs are proline-directed. The consensus amino acid sequence for CDK substrate is (K/R)(S*)PX(K/R), where X denotes any one of the 20 amino acids (2-4) and S* is the phosphorylation site. Phospho-(Ser) CDKs Substrate Antibody recognizes phosphorylated CDK substrates at their consensus motif, providing a powerful tool for CDK target discovery and characterization, as well as HTS drug screening for potential kinase regulators.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information