ARM7535-22C
[Monoclonal Antibody]
ZAP70 Rabbit Monoclonal Antibody (Alexa Fluor(R) 488 Conjugate)
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | FC |
| Immunogen Range: | A synthetic peptide corresponding to residues surrounding the amino terminus of human Zap-70 protein |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 7535 |
| Swiss Prot: | P43403 |
| Synonyms: | FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. |
| Caculated MW: | 70 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
FC 1:50 |
| Reacitivity: | Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information