ARP7293-31
[Polyclonal Antibody]
TNFRSF4 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide of human TNFRSF4 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
7293 |
| Swiss Prot: |
P43489 |
| Synonyms: |
OX40, ACT35, CD134, TXGP1L |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
| Caculated MW: |
29 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:100-1:400
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!