ARMF047-21 [Monoclonal Antibody]
RSK1/RSK2/RSK3 Rabbit Monoclonal Antibody
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Species:   Rabbit
Applications:   WB IP IF
Immunogen Range:   A synthetic peptide corresponding to residues surrounding Asp659 of human p90RSK
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   6195/6196/6197
Swiss Prot:   Q15418/P51812/Q15349
Synonyms:   /
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains (1) and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs) (2). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363, and Thr573, are important for kinase activation (3). RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters (3).
Caculated MW:   90 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
IF 1:25
Reacitivity:   Guinea pig, Human, Monkey, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information