ARP7297P-21
[Polyclonal Antibody]
Phospho-TYK2-Tyr1054/1055 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | A synthetic phosphopeptide corresponding to residues surrounding Tyr1054/1055 of human Tyk2 protein |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 7297 |
| Swiss Prot: | P29597 |
| Synonyms: | JTK1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | Tyk2, a member of the Jak family of protein tyrosine kinases, associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and interferon-alpha and beta (1-3). Following ligand binding, Tyk2 is activated by phosphorylation on Tyr1054 and/or Tyr1055 (4). Tyk2 is required for the tyrosine phosphorylation of Stat3 in the IFN-beta signaling cascade (5). |
| Caculated MW: | 134 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:1000 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information