AMM7299-21S [Monoclonal Antibody]
TYMS Mouse Monoclonal Antibody (IHC Specific)
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Species:   Mouse
Applications:   IHC
Immunogen Range:   A purified recombinant tyrosinase
Clonality:   Monoclonal Antibody
Isotype:   IgG2a
GENE ID:   7299
Swiss Prot:   P14679
Synonyms:   OCA1A, OCAIA, SHEP3
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Tyrosinase, found in the membrane of melanosomes (1), is a key enzyme in the biosynthesis of melanin pigments (1,2). It is a melanocyte differentiation antigen and is expressed in normal melanocytes and malignant melanomas (1,3). Tyrosinase is implicated to be an antigen target for melanoma vaccines (1).
Caculated MW:   70-80 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:200
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information