ARM3630-21C
[Monoclonal Antibody]
INS Rabbit Monoclonal Antibody (Alexa Fluor(R) 488 Conjugate)
www.yhsbio.com
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Species: |
Rabbit |
Applications: |
IF FC |
Immunogen Range: |
A synthetic peptide corresponding to the sequence of human insulin |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG |
GENE ID: |
3630 |
Swiss Prot: |
P01308 |
Synonyms: |
ILPR, IRDN, IDDM2, MODY10, Insulin |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq |
Caculated MW: |
6 kDa |
Observed MW: |
Refer to Figures |
Applications: |
IF 1:200 FC 1:50
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!