ARM5156-23C [Monoclonal Antibody]
PDGFRA Rabbit Monoclonal Antibody (Alexa Fluor(R) 594 Conjugate)
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Species:   Rabbit
Applications:   IF
Immunogen Range:   A recombinant protein corresponding to the PDGF receptor α extracellular domain
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   5156
Swiss Prot:   P16234
Synonyms:   CD140A, MGC74795, PDGFR2, Rhe-PDGFRA
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq
Caculated MW:   190 kDa
Observed MW:   Refer to Figures
Applications:   IF 1:50
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information