ARM3630-22C
[Monoclonal Antibody]
INS Rabbit Monoclonal Antibody (Alexa Fluor(R) 647 Conjugate)
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | FC |
| Immunogen Range: | A synthetic peptide corresponding to the sequence of human insulin |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 3630 |
| Swiss Prot: | P01308 |
| Synonyms: | ILPR, IRDN, IDDM2, MODY10, Insulin |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | The maintenance of glucose homeostasis is an essential physiological process that is regulated by hormones. An elevation in blood glucose levels during feeding stimulates insulin release from pancreatic β cells through a glucose sensing pathway (1). Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Insulin stimulates glucose uptake from blood into skeletal muscle and adipose tissue. Insulin deficiency leads to type 1 diabetes mellitus (2). |
| Caculated MW: | 6 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
FC 1:50 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information