ARM4747-23C
[Monoclonal Antibody]
NEFL Rabbit Monoclonal Antibody (Alexa Fluor(R) 594 Conjugate)
www.yhsbio.com
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Species: |
Rabbit |
Applications: |
IF |
Immunogen Range: |
A synthetic peptide surrounding Glu450 of human Neurofilament-L protein |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG |
GENE ID: |
4747 |
Swiss Prot: |
P07196 |
Synonyms: |
CMT1F, CMT2E, FLJ53642, NF-L, NF68, NFL |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq |
Caculated MW: |
62 kDa |
Observed MW: |
Refer to Figures |
Applications: |
IF 1:50
|
Reacitivity: |
Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!