ARP11140P-21 [Polyclonal Antibody]
Phospho-CDC37-Ser13 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IP
Immunogen Range:   /
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   11140
Swiss Prot:   Q16543
Synonyms:   CDC37A, P50CDC37, Hsp90 co chaperone Cdc37
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Cdc (cell division control) family of proteins are regulatory proteins involved in the processes of cell cycle and proliferation. Cdc37, migrated as a protein of 50 kDa in SDS PAGE, is a co-chaperone protein that recruits several immature client kinases to Hsp90 for proper folding. It functions in association with Hsp90, although little is known of its mechanism of action or where it fits into a folding pathway involving other Hsp90 cochaperones. Cdc37 up-regulation is a common early event in some localized human cancers. But, the effect of Cdc37 dysregulation in human cells is unclear.
Caculated MW:   44 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   /
For research use only. Not intended for diagnostic or therapeutic use!
Additional information