ARM4082P-21 [Monoclonal Antibody]
Phospho-MARCKS-Ser167/170 Rabbit Monoclonal Antibody
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Species:   Rabbit
Applications:   WB IF FC
Immunogen Range:   A synthetic phosphopeptide corresponding to residues surrounding Ser167 and Ser170 of human MARCKS protein
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   4082
Swiss Prot:   P29966
Synonyms:   80K-L, FLJ14368, FLJ90045, MACS, PKCSL, PRKCSL
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Caculated MW:   75 kDa rodent, 80 kDa human
Observed MW:   Refer to Figures
Applications:   WB 1:1000
IF 1:100
FC 1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information