AMM5111-22C [Monoclonal Antibody]
PCNA Mouse Monoclonal Antibody (PE Conjugate)
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Species:   Mouse
Applications:   FC
Immunogen Range:   A recombinant Protein A-PCNA fusion protein obtained from pC2T
Clonality:   Monoclonal Antibody
Isotype:   IgG2a
GENE ID:   5111
Swiss Prot:   P12004
Synonyms:   MGC8367
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Caculated MW:   36 kDa
Observed MW:   Refer to Figures
Applications:   FC 1:50
Reacitivity:   Bovine, Human, Monkey, Mouse, Pig, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information