ARM1072-21C [Monoclonal Antibody]
CFL1 Rabbit Monoclonal Antibody (HRP Conjugate)
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide corresponding to central residues of human cofilin1 protein
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   1072
Swiss Prot:   P23528
Synonyms:   CFL, CFL1, p18, Cofilin 1
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Caculated MW:   19 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   Dog, Human, Monkey, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information