ARM4747-22C [Monoclonal Antibody]
NEFL Rabbit Monoclonal Antibody (Alexa Fluor(R) 555 Conjugate)
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Species:   Rabbit
Applications:   IF
Immunogen Range:   /
Clonality:   Monoclonal Antibody
Isotype:   /
GENE ID:   4747
Swiss Prot:   P07196
Synonyms:   CMT1F, CMT2E, FLJ53642, NF-L, NF68, NFL
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq
Caculated MW:   62 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   /
For research use only. Not intended for diagnostic or therapeutic use!
Additional information