PRP277747-21 [Polyclonal Antibody]
Cre Recombinase Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide corresponding to residues surrounding Asp141 of Cre recombinase protein
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   2777477(Phage)
Swiss Prot:   P06956
Synonyms:   P1_gp003
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Cre recombinase is a bacteriophage-P1 enzyme required for maintenance of the phage genome as a monomeric plasmid in the lysogenic state (1,2). This enzyme mediates a site-specific recombination between two 34 base pair loxP sites. This reaction can be carried out in vitro, indicating that it does not require accessory factors (3). The Cre/Lox system has been used for a number of in vitro and in vivo applications including targeted gene deletions (4) and gene-specific humanized animal models (5). Resolution of the crystal structure of the Cre-Lox complex revealed that two Cre molecules interact with a single Lox site (6).
Caculated MW:   38 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   All
For research use only. Not intended for diagnostic or therapeutic use!
Additional information