ARM367-21C [Monoclonal Antibody]
AR Rabbit Monoclonal Antibody (Alexa Fluor(R) 488 Conjugate)
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Species:   Rabbit
Applications:   IF FC
Immunogen Range:   A recombinant protein corresponding to residues near the amino terminal region of human androgen receptor protein
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   367
Swiss Prot:   P10275
Synonyms:   KD, AIS, TFM, DHTR, SBMA, HYSP1, NR3C4, SMAX1, HUMARA
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3).
Caculated MW:   110 kDa
Observed MW:   Refer to Figures
Applications:   IF 1:50
FC 1:50
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information