ARMF025P-22
[Monoclonal Antibody]
Phospho-SRC-Tyr416 Rabbit Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IP |
| Immunogen Range: | A synthetic phosphopeptide corresponding to residues surrounding Tyr416 of human Src protein |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 2534/3055/3932/4067/6714/7525 |
| Swiss Prot: | P06241/P08631/P06239/P07948/P12931/P07947 |
| Synonyms: | / |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2). |
| Caculated MW: | 60 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:1000 |
| Reacitivity: | Human, Monkey, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information