ARM64223-22C [Monoclonal Antibody]
MLST8 Rabbit Monoclonal Antibody (Sepharose Bead Conjugate)
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Species:   Rabbit
Applications:   IP
Immunogen Range:   /
Clonality:   Monoclonal Antibody
Isotype:   /
GENE ID:   64223
Swiss Prot:   Q9BVC4
Synonyms:   GBL, LST8, MGC111011, POP3, WAT1
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian Target of Rapamycin (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals (1). mTOR is a large protein kinase with two different complexes. One complex contains mTOR, GβL, and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, GβL, and rictor (1). GβL associates with the kinase domain of mTOR and stimulates mTOR kinase activity (2). A reduction in GβL expression has been shown to decrease in vivo phosphorylation of S6K1 (2).
Caculated MW:   36 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   /
For research use only. Not intended for diagnostic or therapeutic use!
Additional information