ARM5460-21S [Monoclonal Antibody]
POU5F1 Rabbit Monoclonal Antibody (ChIP Formulated)
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Species:   Rabbit
Applications:   WB IP
Immunogen Range:   A recombinant protein specific to the amino terminus of human Oct-4A protein
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   5460
Swiss Prot:   Q01860
Synonyms:   MGC22487, OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Caculated MW:   45 kDa
Observed MW:   Refer to Figures
Applications:   ChIP 1:50
Dot 1:50
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information