ARP5747-21C [Polyclonal Antibody]
PTK2 Rabbit Polyclonal Antibody (Biotinylated)
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Species:   Rabbit
Applications:  
Immunogen Range:   /
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   5747
Swiss Prot:   Q05397
Synonyms:   FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Caculated MW:   119 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   /
For research use only. Not intended for diagnostic or therapeutic use!
Additional information