ARM1104P-21
[Monoclonal Antibody]
Phospho-RCC1-Ser11 Rabbit Monoclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide corresponding to residues surrounding Ser11 of human RCC1 protein |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG |
GENE ID: |
1104 |
Swiss Prot: |
P18754 |
Synonyms: |
CHC1, RCC1-I, SNHG3-RCC1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1. |
Caculated MW: |
45 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!