ARM4792P-21C
[Monoclonal Antibody]
Phospho-NFKBIA-Ser32 Rabbit Monoclonal Antibody (Biotinylated)
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic phosphopeptide corresponding to residues surrounding Ser32 of human IκBα |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG |
GENE ID: |
4792 |
Swiss Prot: |
P25963 |
Synonyms: |
IKBA, MAD-3, NFKBI |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |
Caculated MW: |
40 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000
|
Reacitivity: |
Human, Monkey, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!