ARM1965P-21C
[Monoclonal Antibody]
Phospho-EIF2S1-Ser51 Rabbit Monoclonal Antibody (Biotinylated)
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| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic phosphopeptide corresponding to residues surrounding Ser51 of human eIF2α protein |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
1965 |
| Swiss Prot: |
P05198 |
| Synonyms: |
EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S28), and the 52-kD EIF2-gamma subunit (EIF2S3). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha. |
| Caculated MW: |
38 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:1000
|
| Reacitivity: |
D. melanogaster, Human, Monkey, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!