Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human Striatin 3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | |
Swiss Prot: | |
Synonyms: | Striatin3, Striatin-3, Cell cycle autoantigen SG2NA, Cell cycle S/G2 nuclear autoantigen, GS2NA, nuclear autoantigen, S/G2 antigen, SG2NA, Striatin 3, Striatin, calmodulin binding protein 3, STRN3_HUMAN. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |