HRP4792P-21S [Polyclonal Antibody]
Phospho-NFKBIB-Thr19/Ser23 Rabbit Polyclonal Antibody (Human Specific)
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic phosphopeptide corresponding to residues of human IκBβ surrounding Thr19/Ser23
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   4793
Swiss Prot:   Q15653
Synonyms:   IKBB, TRIP9
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Caculated MW:   48 to 50 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information