HRP4792P-21S
[Polyclonal Antibody]
Phospho-NFKBIB-Thr19/Ser23 Rabbit Polyclonal Antibody (Human Specific)
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DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic phosphopeptide corresponding to residues of human IκBβ surrounding Thr19/Ser23 |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
4793 |
Swiss Prot: |
Q15653 |
Synonyms: |
IKBB, TRIP9 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene. |
Caculated MW: |
48 to 50 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!