AMM4792-22S [Monoclonal Antibody]
NFKBIA Mouse Monoclonal Antibody (Amino-terminal Antigen)
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Species:   Mouse
Applications:   WB IHC IP IF FC
Immunogen Range:   A GST-IκBα fusion protein corresponding the amino-terminus of human IκBα
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   4792
Swiss Prot:   P25963
Synonyms:   IKBA, MAD-3, NFKBI
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Caculated MW:   39 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
IHC 1:50
IF 1:125
FC 1:800
Reacitivity:   Bovine, Guinea pig, Human, Monkey, Mouse, Pig, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information