ARP4791P-21 [Polyclonal Antibody]
Phospho-NFKB2-Ser866/870 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IP
Immunogen Range:   A synthetic phosphopeptide corresponding to residues surrounding serines 866/870 of NF-κB2 p100 Nomenclature refers to the human sequence (SwissProt# Q00653) This site is homologous to rat Ser864/868 (Q5U2Z4) and mouse Ser865/869 (Q9WTK5)
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   4791
Swiss Prot:   Q00653
Synonyms:   p52, p105, H2TF1, LYT10, LYT-10, NF-kB2
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.
Caculated MW:   110 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information