Species: | Mouse |
Applications: | WB IHC ELISA IP IF |
Immunogen Range: | A synthetic peptide derived from human IL-6 (51-150aa) |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 |
GENE ID: | 3569 |
Swiss Prot: | P05231 |
Synonyms: | IL6,BSF2,HGF,HSF,IFNB2,IL-6 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. |
Caculated MW: | 23 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:500 IHC 1:100-1:500 IF 1:100-1:500 |
Reacitivity: | Human, Dog, Pig, Cow, Horse, Sheep |