ARP83700-31
[Polyclonal Antibody]
JAM3 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC ELISA IP IF ICC FC |
| Immunogen Range: | synthetic peptide derived from human JAM3 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 83700 |
| Swiss Prot: | Q9BX67 |
| Synonyms: | JAMC, JAM-2, JAM-3, JAM-C |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants. |
| Caculated MW: | 31 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:500 IHC 1:100-1:500 IF 1:100-1:500 ICC 1:100-1:500 FC 1:100-1:500 |
| Reacitivity: | Human, Mouse, Rat, Dog, Pig, Cow, Horse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information