
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from human ACCN5 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | |
| Swiss Prot: | |
| Synonyms: | amiloride sensitive cation channel 5, intestinal, Amiloride sensitive sodium channel;intestine Na+ channel, amiloride-sensitive cation channel 5, HINAC, INAC, ASIC5_HUMAN. |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | ACCN5 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. DEG/ENaC superfamily members are amiloride-sensitive sodium channels that contain intracellular N- and C-termini, two hydrophobic transmembrane regions and a cysteine-containing extracellular loop. Localizing to the cell membrane, ACCN5 is a multi-pass membrane protein that is expressed in small intestine, jejunum and duodenum. ACCN5 is also expressed at low levels in rectum and testis. Existing as a homo- or heterotetramer, ACCN5 functions as a Na+-selective cation channel that, characteristic of its family, can be inhibited by amiloride. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
| Reacitivity: | Human, Mouse, Rat |