
| Species: | Rabbit | 
| Applications: | WB IHC IF | 
| Immunogen Range: | KLH conjugated synthetic peptide derived from human ACCN5 | 
| Clonality: | Polyclonal Antibody | 
| Isotype: | IgG | 
| GENE ID: | |
| Swiss Prot: | |
| Synonyms: | amiloride sensitive cation channel 5, intestinal, Amiloride sensitive sodium channel;intestine Na+ channel, amiloride-sensitive cation channel 5, HINAC, INAC, ASIC5_HUMAN. | 
| Purification: | Purified by Protein A. | 
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Background: | ACCN5 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. DEG/ENaC superfamily members are amiloride-sensitive sodium channels that contain intracellular N- and C-termini, two hydrophobic transmembrane regions and a cysteine-containing extracellular loop. Localizing to the cell membrane, ACCN5 is a multi-pass membrane protein that is expressed in small intestine, jejunum and duodenum. ACCN5 is also expressed at low levels in rectum and testis. Existing as a homo- or heterotetramer, ACCN5 functions as a Na+-selective cation channel that, characteristic of its family, can be inhibited by amiloride. | 
| Caculated MW: | / | 
| Observed MW: | Refer to Figures | 
| Applications: | 
                                WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200  | 
                        
| Reacitivity: | Human, Mouse, Rat |