AMMC002-21C [Monoclonal Antibody]
KRT Mouse Monoclonal Antibody (Alexa Fluor(R) 488 Conjugate)
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Species:   Mouse
Applications:   IF FC
Immunogen Range:   A cytoskeleton preparation from A431 cells
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   3851/3852/3853/3854/3856/3858/3860/3875/286887
Swiss Prot:   P05783/P02538/P04259/P13645/P13646/P19013/P13647/P48668/P05787
Synonyms:   /
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as research biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).
Caculated MW:   46-58 kDa
Observed MW:   Refer to Figures
Applications:   IF 1:100
FC 1:50
Reacitivity:   Human, Monkey, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information