ARM5925P-21C
[Monoclonal Antibody]
Phospho-RB1-Ser807/811 Rabbit Monoclonal Antibody (Alexa Fluor(R) 488 Conjugate)
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | IF FC |
| Immunogen Range: | A synthetic peptide corresponding to residues surrounding Ser807/811 of human Rb protein |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 5925 |
| Swiss Prot: | P06400 |
| Synonyms: | RB, pRb, OSRC, pp110, p105-Rb |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
| Caculated MW: | 110 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
IF 1:800 FC 1:50 |
| Reacitivity: | Human, Monkey, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information