ARP5591P-21
[Polyclonal Antibody]
Phospho-PPKDC-Ser2056 Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide corresponding to residues surrounding Ser2056 of human DNA-PK protein |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
5591 |
Swiss Prot: |
P78527 |
Synonyms: |
DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. |
Caculated MW: |
450 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!