ARP5591P-21
[Polyclonal Antibody]
Phospho-PPKDC-Ser2056 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide corresponding to residues surrounding Ser2056 of human DNA-PK protein |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
5591 |
| Swiss Prot: |
P78527 |
| Synonyms: |
DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. |
| Caculated MW: |
450 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:1000
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!