ARP9531-31
[Polyclonal Antibody]
BAG3 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC ELISA IP IF |
| Immunogen Range: | A synthetic peptide derived from human BAG3 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 9531 |
| Swiss Prot: | O95817 |
| Synonyms: | BIS, MFM6, BAG-3, CAIR-1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
| Caculated MW: | 61 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:500 IHC 1:100-1:500 IF 1:100-1:500 |
| Reacitivity: | Chicken, Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information